Volume 12 - Issue 4


Authors : M.M. Akselrod *, Yu.A. Kotova
Coronary heart disease (CHD) is one of the most common cardiovascular diseases in the world. Numerous studies confirm that it occupies a leading place among causes of death in both developed and developing countries. The key risk factors for the development of CHD are lifestyle, environmental conditions and hereditary predisposition. The presence of these factors in healthy people increases the likelihood of developing the disease in the future.
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Authors : Dr. Simra Arif
Protein S is a vitamin K-dependent plasma glycoprotein that has anticoagulant, anti-inflammatory, and pro-apoptotic activities. It functions as a non-enzymatic cofactor to activated protein C (APC), facilitating the inactivation of clotting factors Va and VIIIa, and is therefore a key player in the anticoagulation pathway. Either inherited or acquired deficiency of Protein S may predispose to venous and less commonly to arterial thrombotic events such as ischemic stroke.
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Authors : O.S. Regentova, O.I. Antonenko, R.A., N.I. Zelinskaya, R.A. Parkhomenko, Rogova T.S. A.I. Shevtsov, M.A. Bliznichenko, V.A. Solodkiy
High grade gliomas (HGG) represent a serious problem for pediatric oncologists. Despite the improvement of the treatment of HGG over the past decades, its results are still far from satisfactory. The purpose of our study was to evaluate the prognostic significance of certain radiological, morphological, and molecular genetic characteristics of the verified brain gliomas on the basis of our own material.
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