Volume 5 - Issue 5


Authors : Andrew Albokrinov
Oculocardiac reflex (OCR) is caused by pressure or traction of intraorbital structures and results in bradycardia. Patients with myocardial hypertrophy can suffer myocardial ischemia due to reduced coronary vascular reserve. In this case report we describe patient who developed myocardial ischemia as a result of OCR induced by traction of intraorbital soft tissue structures during upper blepharoplasty.
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Authors : Fei Yang Chaojie Zou
Moyamoya disease (MMD) is a rare cause of stroke with progressive stenosis of the end of the internal carotid artery and compensatory capillaries. The symptoms and course of moyamoya disease depend on the age of the patient at the time of symptom onset and the type of first episode (ischemic or hemorrhagic), but vary in severity from transient ischemic episodes to persistent neurological deficits [1].
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Authors : Babatope Lanre Awosusi*
Low-grade appendiceal mucinous neoplasm (LAMN) is an uncommon tumor of the appendix with attendant risk of serious complications [1]. It can present with abdominal pain and distention, vomiting, a palpable mass, intestinal obstruction, weight loss, and sometimes intussusception. Other uncommon forms of presentation include hematuria, ureteral obstruction, hydronephrosis, and urinary tract infection [1].
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Authors : Gustavo Frontado*, Andreas Plamper, Karl Rheinwalt
The increasing global prevalence of obesity has led to a higher demand for effective treatment options, with bariatric surgery emerging as a successful intervention for obesity and its associ-ated comorbidities (8,9). Among various bariatric procedures, sleeve gastrectomy (SG) has gained widespread popularity, surpassing the Roux-en-Y gastric bypass (RYGB) as the most frequently performed bariatric surgery worldwide.
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Authors : Qiuhui Yao, Ya Liu, Bo Yang, Jing Wang*
Ovarian cancer ranks high among gynecological malignancies in terms of mortality, necessitating innovative therapeutic strategies [1]. Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis, influencing endothelial cell proliferation, migration, vascular permeability, and apoptosis regulation [2, 3]. While anti-VEGF therapies are prominent in malignancy treatment [4], the significance of cyclin D1 (CCND1) amplification in cancers, including ovarian, cannot be overlooked, as it disrupts the cell cycle, fostering tumorigenesis [5, 6].
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Authors : P. Syamasundar Rao, MD*
During the academic clinical practice for over five decades, the author had the unique opportunity to observe and document many interesting clinical case scenarios. The purpose of this review is to revisit these interesting cases. Because of the voluminous amount of this material, the material may be divided into a five-part series. Each of these case reports, while rare and important clinical observations, do demonstrate a clinical point that is useful to the pediatricians, pediatric cardiologists and/or other physicians.
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Authors : Faiq B. Basa, Stefania Moramarco, Leonardo Emberti Gialloreti
The new coronavirus disease (Covid-19) was initially detected in Wuhan, China, in December 2019 [1]. There are now established Covid-19 cases with neurological symptoms, which developed either through direct harm of the central nervous system (CNS) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or via autoimmune processes [2, 3]. Several neurological complications have been described: encephalitis, meningitis, cerebrovascular diseases, acute disseminated encephalomyelitis (ADEM), and encephalopathies [4, 5].
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Authors : Claude Boscher, Dominique Jordan, Anne Sophie Alonso, Ozlem Erol, Francois Tarragano, Richard Luscan
Erythropoietin (EPO) is a pleiotropic anti-apoptotic, neurotrophic, anti-inflammatory, and pro-angiogenic endogenous agent, in addition to its effect on erythropoiesis. Exogenous EPO is currently used notably in human spinal cord trauma, and pilot studies in ocular diseases have been reported. Its action has been shown in all (neurons, glia, retinal pigment epithelium, and endothelial) retinal cells. Patients affected by the Flammer Syndrome (FS) (secondary to Endothelin (ET)-related endothelial dysfunction) are exposed to ischemic accidents in the microcirculation, notably the retina and optic nerve.
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