Volume 5 - Issue 4


Authors : Gustavo Novaes Lima, Isabela Pereira de Farias, Pedro Henrique Massi, Talita Cristino Cruz Paulino, Raimundo Nonato de Souza Andrade, Wag- ner Ramos Borges*
Diseases of the cardiovascular system have been seen for many years as important factors in the population's illness. According to data from the Ministry of Health, in 1999, such comorbidities led to approximately 1,100,000 hospitalizations through the Unified Health System 1. Within this scenario, Venous Thromboembolism (VTE) stands out, a pathological condition marked by the development of a clot in the veins, which leads to impairment of blood circulation.
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Authors : Abdelaziz Yehya*,MD,Ibrahim Gamaan,MD,YasserAshour MD, Mohamed Elsayed MD, Ahmed Salah, Msc
Primary omental gangrene is a very rare cause of acute abdomen [1].Primary omental gangrene is a condition in which a pedicle of the omental twisted on its longer axis to such an extent that its vascularity is compromised[2]. It occurs because a mobile, thick segment of omentum rotates around a proximal fixed point in the absence of any secondary intra-abdominal pathology [2,3].
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Authors : Rhea Mattar , Fadi El Karak , Ernest Diab * Marwan Ghosn
Colon cancer (CC) represents a significant public health concern due to its high incidence and severity. It ranks among the leading causes of cancer-related morbidity and mortality globally. In terms of frequency, it is the third most commonly diagnosed cancer in men and the second in women. Furthermore, it stands as the third leading cause of cancer-related mortality in both men and woman (1). The survival of CC depends on the stage of the disease at the time of diagnosis and the response to treatment. The 5-year survival rate decreases as the stage increases: it is greater than 90% for stage I and less than 15% for stage IV. Early detection would therefore be important and effective (2). About 90% of patients with CC are treated surgically (3).
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Authors : Xin Liu, Alan Joseph, Ayman Aboda*, Brian McCully
An arteriovenous malformation (AVM) is an anomalous vascular communication between arterial and venous systems that circumvents the normal interposing capillary bed and may lead to shunting of highpressure arterial blood towards low-pressure efferent vessels. The abnormal flow may damage the veins causing complications such as varicosity, pain, swelling and hemorrhage (1) AVMs' dimensions, clinical manifestation, and complexity vary considerably depending on the location, calibre, and complexity of the vessels involved. Head and neck AVMs represent approximately 37.3% of all AVMs, with cerebral AVMs having a prevalence of about 0.01%–0.5% in the population.
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Authors : Antonella Peduto, MD et PhD, Eleonora Barabesi, MD, Maria Chiara Giraudo, MD, Franco Fioretto, MD, Davide Colavito, MS, Alberta Leon, MS, Lorena Sorasio, MD
The prevalence of autism spectrum disorders (ASD) has risen over the last few decades from 2-4 in 10,000 to an estimate of 1 in 100. This is mostly due to changes in the broadening of investigation and diagnostic criteria. There are several rare monogenic diseases in which autism is a trait of neurodevelopment disorder, characterized by cognitive and motor disabilities, language impairment, in association with epilepsy, as well as other psychiatric disorders and distinctive physical features or multiorgan malformations. Some consider these disorders as “syndromic autism” and, among those, Kleefstra syndrome is a rare condition with a heterogenous clinical phenotype which includes autistic- like features. Kleefstra syndrome is caused by haploinsufficiency of EHMT1 (euchromatin histone methyltransferase 1)
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Authors : Mikolajczyk Marek*, Baj Zbigniew, Majewska Ewa
Allergen immunotherapy is a well-established way of treatment in children with allergic rhinitis (AR). The therapy is the only method of changing the natural course of the disease and may prevent new sensitizations (1) (2). Unfortunately, it is not possible to achieve this effect in all allergic patients. To implement the treatment, the following conditions have to occur: no contraindications, good cooperation with patient/parents, correct diagnosis of AR, and access to a specific allergen for immunotherapy (3). Finding the specific allergen which causes allergic symptoms is not easy in some patients, moreover, typical allergy tests, like specific IgE serum measurements or skin prick tests, are not always sufficient.
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Authors : Shahnaz Aali, Hari Yuvaraj H, Ayman Aboda*, Brian McCully
Schistosomiasis, colloquially known as bilharzia or snail fever, is a water borne parasitic disease caused by parasitic trematodes worms belonging to the genus Schistosoma (1,2). It is a disease of global impact, affecting nearly 240 million individuals worldwide, predominantly in impoverished rural and peri-urban areas of Sub-Saharan Africa, South America and Asia (3). It is the second most common infection after malaria (4). Schistosomes have a complex life cycle involving specific freshwater snail species as intermediate hosts and humans as the definitive hosts
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Authors : Justine Pinckers, MD, Katty Delbecque, MD, Frédéric Kridelka MD&PhD, Frédéric Goffin MD&PhD*
Borderline ovarian tumor (BOT) is a non-invasive neoplasm. Primitive peritoneal borderline tumor is histologically similar to non-invasive peritoneal implant of an ovarian serous borderline tumor. BOT carry out a favorable prognosis even at advanced stages. They are often diagnosed in women of childbearing age, so fertility is an important consideration in planning treatment. More welldesigned clinical trials are needed to determine the feasibility of fertility sparing surgery in treating advanced stage BOT according to the International Federation of Gynecology and Obstetrics (FIGO) classification.
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Authors : Shahnaz Aali, Hari Yuvaraj H, Ayman Aboda*, Brian McCully
Schistosomiasis, colloquially known as bilharzia or snail fever, is a water borne parasitic disease caused by parasitic trematodes worms belonging to the genus Schistosoma (1,2). It is a disease of global impact, affecting nearly 240 million individuals worldwide, predominantly in impoverished rural and peri-urban areas of Sub-Saharan Africa, South America and Asia (3). It is the second most common infection after malaria (4). Schistosomes have a complex life cycle involving specific freshwater snail species as intermediate hosts and humans as the definitive hosts. Human infection typically occurs during routine agricultural, domestic, and recreational activities that expose individuals to infested water contaminated with the free-swimming larval form, cercariae (5).
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