Volume 5 - Issue 3
Authors : Manar Al Sanaa Al Zeedi*
Coronavirus disease 2019 (COVID-19)—a respiratory illness caused by a recently identified, highly transmissible virus known as severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2)—has had considerable global morbidity and mortality.1,2 As a result, a number of anti-SARS-CoV-2 vaccines have been
developed with unprecedented speed.3 While these vaccines have satisfactory efficacy and safety profiles, experience with their use is undeniably limited.4,5
Accordingly, additional knowledge of rare side-effects is important to inform future recommendations.
Authors : Dong Wei, Shi Changsong*
Legionella pneumophila is a pathogen widely found in artificial water environment conditions and is one of the main pathogens causing legionella
pneumophila pneumonia, with a mortality rate of up to 30% [1]. Legionella long beach is mainly transmitted through fertile soil and compost. Currently,
reported cases of legionella long beach are very rare in China, but it is the most common type of community-acquired pneumonia in Australia and New
Zealand,of which clinical manifestations are not easily distinguishable from legionella pneumophila[2].
Authors : Dr Vishnu Sharma MBBS, MD, DM , Dr Naman Modi MBBS, Mr Vansh Bagrodia
Hydroxyurea, a cytotoxic agent commonly employed in the treatment of myeloproliferative disorders, has been linked to various dermatological
manifestations, including the infrequent occurrence of leg ulcers. We present a case of a middle-aged male patient with a medical history of primary
myelofibrosis, who presented with multiple painful leg ulcers secondary to hydroxyurea therapy. This case underscores the critical significance of
comprehensive literature review and meticulous evaluation to identify and manage adverse events associated with hydroxyurea therapy.
Authors : Deng Jingqi, MS & RN
Anaphylactic shock resulting from encounters with insects has been reported in various regions worldwide, including the Americas, Australia, Asia,
and Europe, but limited reports exist from West Africa. This case highlights the challenges in promptly diagnosing anaphylactic shock, particularly when
respiratory depression and respiratory arrest occur. The patient's proximity to a large comprehensive hospital played a crucial role in facilitating immediate
medical intervention. However, the unavailability of essential emergency medications, such as adrenaline, in resource-limited settings like Sierra Leone
can lead to delayed treatment.
Authors : T. J. Hart, Chloe Engler Hart, Aaryn S. Frewing, Dr. Paul M. Urie M.D./
Ph.D., Dr. Dennis Della Corte Dr. rer. nat.*
Advances in image recognition enable AI algorithms to better classify and annotate images in pathology.1 This has spurred the development of algorithms
to assist pathologists in detecting and diagnosing prostate adenocarcinoma.2,3 Future AI assistants could augment the basic task of image annotation and
Gleason pattern assignment.
Authors : Nwodo Miriam U., Isomah Chiladi, J*., Dodoru, Tuemi Robinson, Abiye Chiladi Isomah, Walter Olivia, E., Ukpong, Martha F.
Despite HBV being endemic or hyper endemic in Africa, there is paucity of data on the genotypes and their distribution in this part of the country. This study is
aimed at detecting the prevalent genotypes of HBV among patients attending two tertiary hospitals in Yenagoa, Nigeria. A total of 656 patients [females
475(72.4%) and males 181(27.6%)] were tested for Hepatitis B surface antigen (HBsAg) between the period of January to June 2022. Blood samples collected
were analyzed using immunochromatography techniques for HBsAg detection and multiplex Polymerase chain reaction (PCR) using type-specific primers for
genotyping.
Authors : Dr. Muneerah Khalid Aljadidi*, Dr. Turki Faheem Alshammari
Verocay, in 1910, was the first to describe a benign rare neoplasm of ectodermic origin growing from the neural sheath and characterized by the
presence of Verocay corpuscles (Baig et al., 2019). This growth, later known as schwannoma, is a tumor originating from the Schwann cells of the nerve sheath
of the peripheral nervous system.
Authors : Hamid Mokhtari Torshizi, Negar Omidi, Mohammad Rafie Khorgami, Fattaneh Khalaj, Mohsen Ahmadi*
As one of the main electrolytes, potassium plays an important role in cellular membrane potential variations, especially in the heart (1). Normal
cardiac function depends on regular sequential cardiac myocyte depolarization and repolarization. Any disruption in this circle may lead to cardiac conduction
disorders and severe arrhythmia. The manifestation of these changes in the ECG signal is usually related to potassium concentration measured as potassium
blood level (2). Children with cardiac and kidney diseases are more susceptible to the effects of potassium changes (3).
Authors : Luis López-Flores*, MD, Rocío Cózar-León, MD, PhD, Ernesto Díaz-Infan-te, MD, PhD
A 54-year-old woman with hypertension presented to the emergency department after syncope occurred during prolonged standing. On arrival,
heart rate and blood pressure were normal. Admission electrocardiogram (Figure 1, A) showed sinus rhythm at 55 bpm, PR 200 ms, a wide QRS complex
with morphology of complete right bundle branch block (width 180 ms), with small electrical potentials immediately after the QRS in all leads, more
variegated in right precordial leads – findings suggestive of epsilon wave-, and a negative T wave in all precordial leads.
Authors : Shaozhi Xi MD, Xiangnan Li MM, Shuibo He MM, Zhong Yi MD*
Fragmented QRS (fQRS) on the 12-lead electrocardiogram (ECG) is defined as the presence of additional notches buried within the QRS, which is widely
accepted as a sign of myocardial infarction scar or fibrosis. [1, 2] The fQRS is derived from the abnormality of ventricular depolarization due to ventricular
heterogeneity and derangement of ventricular conduction around the infarction zone or scar. [3-5] And the fQRS is also a sign of left ventricular desynchronization
in patients of heart failure with reduced ejection fraction (HFrEF) and the narrow QRS complex (<150 ms). [6] A meta-analysis showed that fQRS on
patient’s baseline ECG increased all-cause mortality and major arrhythmic events in HFrEF patients