Volume 2 - Issue 3
Authors : Fawaz F. Alshammrie* , May Obaid Alnawmasi
Psoriasis is a lifelong inflammatory dermatosis related to an anomaly of
the proliferation and differentiation of epidermal cells. It is a chronic non-
infectious disease that affects people of all ages [1]. A growing number of
population-based studies provide prevalence estimates of psoriasis worldwide
[2-6]. Although children present with the same clinical subtypes of psoriasis
seen in adults, lesions may differ in distribution and morphology; hence, their
clinical symptoms at presentation may vary from those reported by adults
[7]. Although the diagnosis of psoriasis is primarily based on clinical features,
biopsy can therefore help diagnose children with atypical presentations [8,9].
Authors : María de Miguel, MD, Paloma Pulido, MD, Gonzalo Cabezón, MD, Javier López, MD, PhD, J. Alberto San Román, MD, PhD
A 45-years old male with history of diabetes was admitted with generalized
myalgia, asthenia and fever within the last week. No dental procedures neither
intravenous drug use were referred. Physical examination showed normal
central venous pressure, a systolic mitral murmur and limb oedemas. Empiric
antibiotic therapy with linezolid, meropenem and amikacin was initiated.
Authors : Yusak Mangara Tua Siahaan*, MD, PhD, Reza Stevano, MD, Anyeliria Sutanto, MD
As autoimmune conditions share similar environmental, genetic, and
immunological factors in their pathogenesis, patients with one condition are
susceptible to developing additional autoimmune conditions[1]. Myasthenia
gravis (MG) and systemic lupus erythematosus (SLE) constitute two distinct
autoimmune diseases that share common risk factors and often manifest in
young women[2]. However, simultaneous occurrence in the same patient
is rare. MG is characterized by generalized muscle weakness secondary to
neuromuscular junction (NMJ) transmission impairment due to the presence
of autoantibodies against postsynaptic acetylcholine receptors (AchRs)[3].
Authors : Dr Yu Feng Shi*, Dr Sameer Malik
Human Immunodeficiency Virus (HIV) is the cause of one of the most
significant global pandemics in the 20th and 21st centuries with just under fifty
million fatalities and an estimated 0.7% of adults worldwide between 15-49
years living with the virus or around 37.7 million people1.HIV infection can present in a myriad of ways ranging from asymptomatic, a
mononucleosis type of syndrome to various mucocutaneous, gastrointestinal and neurological presentations.
Authors : Claudia (Chunyun) Wang PhD, Hongtao Li, PhD*
This review presents the current scientific evidence of the health benefits
of Tai Chi (TC), a form of mind-body exercise. In our world characterized by a rise
in the proportion of older people, of people with chronic diseases, and of obese
people, the most widely agreed on recommendation to maintain the health of
the society is exercise. TC is considered a mild to moderate form of exercise as
judged by the energy expenditure of 1.5 to 4.6 metabolic equivalents (METs).1
In comparison, swimming has 4.5 to 10 METs and running 6 to 16 METs. It also
has low impact on the joints. Hence, TC has been suggested as a good fit for
the sedentary population and the population with chronic disease, which both
often deal with physical barriers to increase their physical activity.2 Moreover,
TC can be done without special equipment or minimal space requirement,
which makes it suitable for people with economical barriers.
Authors : Saeed Shoja Shafti MD
Let’s start with this approximate question: why should an inhabitant,
for example, a middle-class youngster, take a gun and kill his fellow citizens,
neighbors, friends or classmates, with annihilation or termination of his own life,
instead of working, loving, enjoying and teaming up with them ? What turns a
former kind neighbor into a future foe? Mass shooting is a serious problem that
usually has intricate ins and outs, which have roots in a mixture of sociological,
cultural, historical, anthropological and psychological bases, and, so, demands
a systematic approach, instead of the customary descriptive psychiatric
approach or a merely criminological attitude. Sociologically, it seems that when
overt public processes are not synchronizing with each other or covert societal
courses, and so, may flare up a series of social clashes or cognitive dissonances,
a confounding dynamic arises which may lead to improper discharges by
irritated, defiant or despairing people.
Authors : Plotnikova I.A, Troitskaya LA, Zelentsova V.L, Stepina D.A., Shtanova A.A
Vitamin B6-dependent epilepsies are aheterogeneous group of autosomal
recessive diseases that are caused by mutations of five different genes involved
in vitamin B6 metabolism [1]. Vitamin B6 is present in many forms in the human
diet, but only pyridoxal-5 -phosphate (PLP) plays a vital role in the metabolism
of a number of neurotransmitters, especially the inhibitory mediator gamma-
aminobutyric acid. Code errors leading to a lack of pyridoxal-5'-phosphate
manifest as B6-dependent epilepsy, including pyridoxamine-5-phosphate
oxidase (PNPO) deficiency, which affects the synthesis and recycling of pyridoxal5'-phosphate [2,3].
Authors : Akbar Rasekhi Kazerooni, MD. Keyvan Nowrouzi, MD. Faezeh Sehatpour*, MD.MPH.
The Covid-19 pandemic is an ongoing pandemic that started in December
2019 and spread rapidly around the word. COVID-19 was caused by severe acute
respiratory syndrome corona virus 2 (SARS-CoV-2), first identified in Wuhan,
China. So far, more than 200 countries have been affected by the pandemic.
Authors : Mohamed Adbellahi Cheikh Ahmed*; Sidi Sidi Cheikh ; Mohamed Jiddou Sidi Baba
Morning glory syndrome is a birth defect that affects the optic nerve of the eye. The morning glory syndrome (MGS) or morning glory disc anomaly was named
by Kindler in 1970 because of its resemblance to the morning glory flower.
Morning glory syndrome can be associated with midline cranial defects and
abnormal carotid circulation. We report the case of a 10-year-old adolescent,
who was brought by his parents for a profound bilateral visual acuity decrease
since birth. Ophthalmic examination revealed bilateral morning glory
syndrome.