Adverse Drug Reactions Awareness Among Sample of People in Northern Region, Saudi Arabia
Fawwaz Freih Alshammarie1*, Yasmeen Ali Muraizeq2, Rahaf Turki Aldhaban2, Asma Mohammed Almutairi2, Monerah Thaar Alshammari2
1Assistant Professor, Department of Dermatology, College of Medicine, University of Hail, Hail, Saudi Arabia.
2Medical student, College of Medicine, University of Hail, Hail, Saudi Arabia.
*Fawwaz Freih Alshammarie, Assistant Professor, Department of Dermatology, College of Medicine, University of Hail, Hail, Saudi Arabia
Figure 1: Demographic factors, descriptive of demographic information
As shown in Figure (1) Demographic factors, 475 people participated in this study including 382 female (80.4%) and 93 males (19.6%) (p<0.05). Their age ware ranged between less than 16 and more than 35 with advantage for age group more than 35 (42.90%).
Table 1: Drug reactions: Descriptive analysis (n=475)
As shown in Table (1) Drug reactions only 43 (9.1%) had drug allergy (p<0.01). The participants were asked about the medication kinds that they have been used with the reaction which show the highest for Antibiotics (53.5%), other show less like: NSAI drugs (2.3%), Antiepilepsy (0%), Analgesics (18.6%), Vitamins (7%), Insulin (2.3%), Aspirin (11.6%), Herbal (16.3%) and other (14%). Antibiotics reported insignificant (p>0.05) and Antiepilepsy not used. The rest kinds only ranged between 8 (18.6%) to one (2.3%) of using (p<0.01). Also, the symptoms that might participants have been stated such as Rash, Skin heat, Itching, Fever, Cough, Shortness of breath, Anaphylaxis, Swelling (mouth - lips - tongue - eyes), Eye tears , Runny nose, Light headiness and Others, it was clear that they did have that much symptoms as it ranged between only 13(30.2%) for itchiness to 22(51.2%) for Fever (p<0.01), rash and itching were insignificant (p>0.05). Starting Immediately after taking drug was insignificant (p>0.01), 15 (34.9%) indicated that starts hours, to 1 (2.3%) starts in months (p<0.01), although the symptoms were not much among the participants, however, it is clear that starts short time more than long time. The participants reported their time of a health intervention, ranged between once 16(37.2%) which is the highest to 3 times 1(2.3%) (p<0.05).
Table 2: Descriptive analysis (n=475)
Figure 2: Drug reactions detection.
As shown in Table (2) and Figure (2) knowledge, 83.6% of participants were aware, 56.2% agreed that all the body is affected in drug reaction (p<0.05), then face (34.3%) follows by lips (14.1%). Tongue is lowest one with 6.7% (p<0.05). It is clear that the family history of drug reaction is very small ranged between 8.8% for children and 1.9% for father (p<0.05). 59.6% of Participants did not think that drug reaction is hereditary (p<0.05), however 48.1% thought that drug reaction leads to death (p>0.05). As shown in Figure (2) Drug reactions detection, 50.9% had previous skin general allergy test (p>0.05), and 90.9% reported that they test accurate in identifying the drug (p>0.01). Only 10.7% had experience an allergy after negative test’s result (p<0.05). 21.3% had a previous blood test for an allergy (p<0.01) and just 28% took an allergy's injection vaccine. (p<0.01).
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